💉 Semaglutide 20 Week Titration Dosing Protocols
Semaglutide GLP-1 20-Week Titration Treatment
(Includes Medication and injection supplies.)

🌟 PROTOCOL #1: Standard Titration Dosing
Summary: This protocol is for those who can tolerate significant increases in dosing. Patients will use the same single dose for 4 weeks at a time, and continue titrating up until they find the dose that is the most effective for them.
| Treatment Weeks | Single Weekly Injection Dose | Duration at Dose |
| Weeks 1 – 4 | 5 units | 4 weeks |
| Weeks 5 – 8 | 10 units | 4 weeks |
| Weeks 9 – 12 | 15 units | 4 weeks |
| Weeks 13 – 16 | 20 units | 4 weeks |
| Weeks 17 – 20 | 25 units | 4 weeks |
✨ PROTOCOL #2: Optimal Titration Dosing
Summary: This protocol is optimal for those beginning GLP-1 Semaglutide Treatment, using two smaller injections per week for smoother titration.
| Treatment Weeks | Dose Per Injection | Injections Per Week | Total Weekly Units |
| Weeks 1 – 4 | 2.5 units | 2 times | 5 units |
| Weeks 5 – 9 | 5 units | 2 times | 10 units |
| Weeks 10 – 14 | 7.5 units | 2 times | 15 units |
| Weeks 15 – 20 | 10 units | 2 times | 20 units |
| Weeks 21 – 25 | 12.5 units | 2 times | 25 units |
🐢 PROTOCOL #3 Escalating Dose Regimen
Summary: This protocol provides a consistently increasing dose to help you find the exact dose that works best for you.
| Treatment Week | Single Weekly Injection Dose |
| Week 1 | 7 units |
| Week 2 | 10 units |
| Week 3 | 12 units |
| Week 4 | 14 units |
| Week 5 | 15 units |
| Week 6 | 16 units |
| Week 7 | 17 units |
| Week 8 | 18 units |
| Week 9 | 19 units |
| Week 10 | 20 units |
Weeks 11-20
For Weeks 11-20, you would continue to add only 1-2 units per week until you find the dose you feel is most effective.
If you feel any mild side effects during this titration dosing cycle (such as nausea, diarrhea, or not being hungry at all):
- Do not increase the dose.
- Repeat the same dose the following week.
- Continue at that same dose until those side effects subside.
- After side effects subside, continue back onto the dosing schedule (adding 1 unit every week).
- Maximum Dose: You should never exceed doses beyond 50 units with this medication.
⚠️ Important Dosing Guidelines
- Maximum Dose: You should never exceed doses beyond 50 units with this medication.
- Side Effects: If you feel any mild side effects during this titration dosing cycle (such as nausea, diarrhea, or not being hungry at all):
- Do not increase the dose.
- Repeat the same dose the following week.
- Continue at that same dose until those side effects subside.
- After side effects subside, continue back onto the dosing schedule.
- Note: It is not uncommon to be at a single dose for several weeks or even months.
- Aggressive Adjustments: If you are tolerating the medication well and want to make more aggressive dose adjustments, speak to your Superior Genetix Patient Support Team for guidance.
How To Read ½ (.5) units on a 50 Unit Syringe


